Defiance is an unincorporated town in Saint Charles County, in central-eastern Missouri. The Katy Trail State Park, the final home of Daniel Boone, runs through Defiance near the Missouri River. Boone settled on a Spanish Land Grant in the Femme Osage Valley in 1799, although the community had not been named yet during Boone’s lifetime. The Boone Homestead is situated along Highway F, and is open to the public. Defiance is known for its wineries, as there are several of them between Defiance and Mathasville, in an area sometimes known as the Missouri Weinstrasse, part of the Missouri Rhineland, with vineyards on both sides of the Missouri River. While agriculture and winemaking was the primary focus of the area’s economy, Defiance also included mills, quarries, stockyards, and other businesses. Tradition has it that Defiance was named for its opposition to the town of Matson in the late 1800s, when both towns were competing for a train depot along the Missouri, Kansas and Texas Railroad, which played a large part in the economy of the region. Defiance is north of Matson, east of Femme Osage, and south of the August A. Busch Memorial Conservation Area.
 
 
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Founded in 2008, Chandler Hill is located in Defiance, within the Missouri wine region. The winery and its products are highlighted, including its wine club, a schedule of music and events, wedding accommodations, dining facilities, and shopping venues.
http://www.chandlerhillvineyards.com/
Crossroads Veterinary Hospital
Located in Defiance, Missouri, the animal hospital is a full service veterinary medical facility for companion animals, offering in-house and at-home veterinary care. Its services are discussed, along with its location, office hours, and appointment policies.
http://www.crossroads-vet.com/
Offering food and drinks, the restaurant is sitauted on Highway 94 South in Defiance, Missouri. Its location is given, along with a menu, calendar of events, photographs, and contacts.
http://www.defianceroadhouse.net/
Maintained by the Defiance Merchants Association, the site offers a guide to the area, highlighting local wineries, lodging accommodations, restaurants, recreational opportunities, attractions, and events, along with a profile of the community.
http://www.defiancemo.com/
Situated in Defiance, down the street from the Daniel Boone Home and the Katy Trail, in the Missouri wine country, the B&B offers three guest suites, a seasonal swimming pool, hot tub, inside an outside fireplaces, and several outside dining areas. Its rooms are highlighted, with rates, special offers, and customer testimonials.
http://www.defiancebandb.com/
Open June 1st through November 15th, and based in Defiance, Missouri, the business offers canoe, kayak, and large raft rentals, for Missouri River excursions, following the path taken by the Lewis and Clark Expedition. Photographs, contacts, and other details are presented.
http://www.floatmissouririver.com/
Parson’s House Bed and Breakfast
Built in 1842, and restored in 1986, the B&B facility is situated on a hill in Defiance, overlooking the Missouri River Valley. An overview of the facilities and guest accommodations are featured, with a gallery of photographs and online bookings.
http://www.parsonshousebandb.com/
Formerly operated as Boone Country Winery, the winery is situated on a hill overlooking the Missouri River Valley in Defiance, Missouri. A profile of the business, its products, events, and wedding and event accommodations are featured, with photographs and a blog.
http://www.sugarcreekwines.com/
The bed and breakfast guest lodging facility is situated on Defiance Road in Defiance, Missouri, offering a choice of three rooms or one suite. The accommodations, breakfast facilities, rates, packages, and a calendar of events are featured, and reservations may be made through the site.
http://www.thedefianceinn.com/
The 60-acre facility in Defiance, Missouri offers boarding services for cats and dogs, featuring two lakes and six different yard areas, with accommodations for all breeds. Obedience training is also offered. Its location, rates and requirements are noted.
http://www.sorensonkennels.calls.net/
Set on forty-two acres in the Missouri River Valley, the Defiance, Missouri facility hosts weddings, receptions, corporate retreats, and offers outdoor dining. The restaurant’s location, hours, menus, and wine list are posted, along with event planning and contact data.
http://www.winecountrygardens.net/
Yellow Farmhouse Vineyard & Winery
Offering a selection of wines as well as music events, the winery in Defiance, Missouri is featured, including its tasting room, wine club, an online store, contact data, and a blog. News and announcements are posted to the site.
http://yellowfarmhousewines.com/