Tumor necrosis factor (TNF) inhibitors have proven highly effective against a number of autoimmune diseases, largely due to the fact that biological agents are inherently immunogenic.
Recommended Resources
Managing Patients Taking Tumour Necrosis Factor Inhibitors
Addresses the use of tumor necrosis factor inhibitors in patients with rheumatoid, psoriatic, or juvenile chronic arthritis as well as ankylosing spondylitis who are not responsive to standard antirheumatic drugs.
http://www.australianprescriber.com/magazine/29/3/67/70/
Tumor necrosis factor-alpha Inhibitors: An Overview of Adverse Effects
Contains a review of TNFs and the TNF technology, including a list of possible effects including injection site reactions, infections, induction of autoimmunity, and heart failure.
http://www.uptodate.com/patients/content/topic.do?topicKey=~YHTfYEyr4cy64M&selectedTitle=2%7E150&source=search_result
Tumor Necrosit Factor Inhibitors for the Treatment of Asthma
Exposes the details about TNF in the treatment of chronic airway inflammation and asthma, which takes advantage of the pro-inflammatory mediator inherent in tumor necrosis factor inhibitors.
http://www.springerlink.com/content/432u137x48640322/
